Your backbone, or spine, is made up of 26 bones called vertebrae. In between them are soft discs filled with a jelly-like substance. These discs cushion the vertebrae and keep them in place. As you ...

Herniated disc is said to occur when the intervertebral disc between the two vertebrae of the spine protrudes or herniates into the spinal canal and compresses the spinal nerves that travel through ...

Herniated discs in the lower (lumbar) spine most often result from avulsion (separation) of the tissue connection between the disc and spinal bone, rather than rupture of the disc itself. Herniated ...

A bulging disc in your lower back is most often caused by naturally occurring changes as you age. Most bulging discs don’t cause symptoms, but they may progress to become herniated discs. Lower back ...

This Journal feature begins with a case vignette highlighting a common clinical problem. Evidence supporting various strategies is then presented, followed by a review of formal guidelines, when they ...

Even if you don’t know exactly what a herniated disc is, it just sounds like something you’d want to avoid. That makes perfect sense, because this health issue can be pretty freaking painful—but in a ...

This integrated approach, combining histological analysis and single-nucleus RNA sequencing, revealed that the senescence and depletion of nucleus pulposus progenitor cells (NPPCs) represent ...