Glutamate receptors, including AMPA and NMDA subtypes, are pivotal mediators of excitatory transmission and plasticity across the mammalian central nervous system. Their regulation, which involves ...

In a study published in Cell, a research team led by Zhu Shujia from the Center for Excellence in Brain Science and Intelligence Technology of the Chinese Academy of Sciences (CAS), along with Li Yang ...

When it comes to brain proteins, small changes can make a dramatic difference. Researchers studying NMDA (N-methyl-D-aspartate) receptors, which are essential for learning, memory and moment-by-moment ...

Alzheimer's disease (AD) is a neurodegenerative disorder characterized by progressive memory loss and a decline in mental ...

In the intricate chemical symphony of the brain, glutamate stands as the principal conductor. As the brain's most abundant excitatory neurotransmitter, glutamate facilitates our ability to learn, form ...

Neurotransmitters are the words our brain cells use to communicate with one another. For years, researchers relied on tools that provided limited temporal and spatial resolution to track changes in ...

Three distinct snapshots obtained with cryo-electron microscopy illustrate the arrangement of two of the four symmetrical subunits that make a functional NMDA receptor. During activation, as the ...