Healthy human red blood cells (RBCs) gradually degrade over their lifespan of ~120 days. However, sickle cells - RBCs from sickle cell disease (SCD) patients - degrade much faster within their ...

THE danger of high-altitude flying to patients with sicklemia, until lately, has been more theoretical than.real. As recently as 1951 Margolies 1 said that "the sickle cell trait is not a ...

Researchers have designed a microfluidic device, or 'spleen-on-a-chip,' that can model how the spleen's filters become clogged by sickled red blood cells, leading to a life-threatening condition known ...

September Is Sickle Cell Awareness Month. While many people are familiar with sickle cell anemia, sickle cell traits have also plagued our community. Sickle cell trait (SCT) is an inherited blood ...

Durable expression of anti-sickling fetal hemoglobin and reduction in sickle hemoglobin ob ...

Sickle cell anemia causes sickle-shaped cells to block blood flow to the lungs, leading to acute chest syndrome. Common treatment methods involve oxygen supplementation and pain management. Sickle ...

People often consider sickle cell anemia (SCA) to be a potentially lethal condition. Although SCA often lowers life expectancy, recent advancements in care mean the outlook for those with this ...

Sickle cell disease (SCD) is a group of genetic blood disorders. A person inherits SCD from their parents when they inherit two copies of the sickle cell gene, one from each parent. This hereditary ...

CAMBRIDGE, MA -- Every day, billions of red blood cells pass through the spleen, an organ that is responsible for filtering out old or damaged blood cells. This task is made more difficult when the ...