Calcium is essential for the correct functioning of the cell and requires regulation to avoid high concentrations causing cell death. Calcium ions are important for cell signaling as the binding of ...

Plasmodium falciparum causes malaria in humans by multiplying first in the liver cells and then in red blood cells. Merozoites or daughter parasites are released as the host cells are destroyed to ...

KAE609 (cipargamin; formerly NITD609, Novartis Institute for Tropical Diseases) is a new synthetic antimalarial spiroindolone analogue with potent, dose-dependent antimalarial activity against asexual ...

Plasmodium falciparum is responsible for the most virulent form of human malaria. This protozoan parasite spends part of its lifecycle inside the red blood cells (RBCs) of its host. The mature human ...