Plasmodium falciparum causes malaria in humans by multiplying first in the liver cells and then in red blood cells. Merozoites or daughter parasites are released as the host cells are destroyed to ...

Malaria is a serious public health burden that causes an estimated 1–2 million deaths and 300–500 million infections each year 1. There is no effective vaccine available, and parasites resistant to ...

Calcium is essential for the correct functioning of the cell and requires regulation to avoid high concentrations causing cell death. Calcium ions are important for cell signaling as the binding of ...

Plasmodium falciparum incidence 2000-2017 The Malaria Atlas Project Enlarge image New high-resolution maps of malaria impact highlight global efforts against the disease, identifying areas, including ...

A major tool against malaria in Africa has been the use of rapid diagnostic tests, which have been part of the 'test-treat-track' strategy in Ethiopia, the second most-populated country in Africa. But ...

An effective vaccine for malaria is urgently needed. Naturally acquired immunity to malaria develops slowly, and induction of protection in humans can be achieved artificially by the inoculation of ...

Findings from two early clinical studies suggest a new dual-action antimalarial drug candidate is well tolerated in humans.

Scientists have identified the regional character to Plasmodium falciparum across Africa. Malaria, infecting 219 million individuals in 2017, remains a threat to public health and regional stability.

One might envision a microscopic creature with its very own built-in engine, an engine whose power is fueled by something ...

Swine flu has made the world all too aware of the possibility of diseases making the leap from animal hosts to human ones. Now, we know that another disease made a similar transition from chimpanzees ...

Several million years ago, Plasmodium falciparum – the parasite that causes most cases of human malaria – jumped into humans from other apes. We’ve known as much for decades but for all this time, ...