"It's not intuitive to think the most prevalent receptor for the major neurotransmitter in the brain is also present in the lens," senior investigator Peter Frederikse, PhD, from the University of ...

Glutamate receptors, including AMPA and NMDA subtypes, are pivotal mediators of excitatory transmission and plasticity across the mammalian central nervous system. Their regulation, which involves ...

Metabotropic glutamate receptors (mGluRs) are a diverse family of G protein‐coupled receptors that modulate synaptic transmission and neural excitability in the central nervous system. Their role ...

In a study published in Cell, a research team led by Zhu Shujia from the Center for Excellence in Brain Science and Intelligence Technology of the Chinese Academy of Sciences (CAS), along with Li Yang ...

The most common type of brain tumor in children, pilocytic astrocytoma (PA), accounts for about 15% of all pediatric brain tumors. Although this type of tumor is usually not life-threatening, the ...

Rubio, M.D., Drummond, J.B., and Meador-Woodruff, J.H. Glutamate Receptor Abnormalities in Schizophrenia: Implications for Innovative Treatments. Biomolecules and ...

The brain’s cerebellum plays a key role in coordinating movement, balance, and cognition. Injury to the cerebellum can have a profound impact on basic motor skills, such as sitting, standing, and ...

For decades, the scientific theory of depression focused on chemicals — serotonin, norepinephrine and dopamine. Nearly every ...

Scientists have uncovered a surprisingly large reserve of “silent synapses” in the adult brain—unused neural connections that can be rapidly activated to store new memories.