Antibiotic resistance is racing toward a global crisis, with “superbugs” projected to cause over 10 million deaths annually ...

Antibiotic resistance (AR) has steadily accelerated in recent years to become a global health crisis. As deadly bacteria evolve new ways to elude drug treatments for a variety of illnesses, a growing ...

A comprehensive review explores how bacteria resist phage therapy and offers innovative solutions to combat this challenge. The authors discuss mechanisms like CRISPR-Cas and biofilm formation, and ...

Active Genetics (Pro-AG) exploits a naturally created bacterial mating tunnel between cells to inactivate antibiotic resistance.

Bacteria get invaded by viruses called phages. Scientists are studying how bacteria use CRISPR to defend themselves from phages, which will inform new phage-based treatments for bacterial infections ...

Researchers have identified an unusual arabinose-based modification of bacteriophage DNA that helps viruses evade bacterial ...

Bacteria combat phage infection using antiphage systems and many systems generate nucleotide-derived second messengers upon infection that activate effector proteins to mediate immunity. Phages ...

CRISPR-Cas 9 is a gene-editing tool that made it possible to rewrite any organism's genetic code and tackle genetic diseases more effectively. Known as genetic scissors, CRISPR identifies a DNA ...

In nature, the best-known CRISPR system, CRISPR-Cas9, cuts any RNA or DNA it recognizes as foreign, and thereby protects bacteria from viral attacks. Another CRISPR system, one that is relatively ...