Scientists reveal how sleep protects brain cells, manages metabolic damage, and may help explain links to Alzheimer’s disease ...

When HHMI Investigator Amita Sehgal started studying sleep 25 years ago, the topic elicited a yawn from most biologists. "In the year 2000, if I had suggested to my department that we hire people ...

"You need those neurons to be functional, and for them to be functional, they need a reliable internal source of clean energy," Sehgal explained. "One of the ways that sleep helps the neurons stay ...

New research finds that sleep is essential for protecting brain mitochondria by transferring toxic metabolic waste from neurons to glial cells for disposal.

A research team has discovered a novel mechanism essential for initiating autophagy. The study highlights the role of ZDHHC13, an enzyme that palmitoylates ULK1, in triggering autophagy. This ...